| Educational guide Faculty of Chemistry |
english |
| Bachelor's Degree in Biochemistry and Molecular Biology (2009) |
 Subjects |
| BIOCHEMISTRY |
| Contents |
| IDENTIFYING DATA | 2019_20 |
| Subject | BIOCHEMISTRY | Code | 13214008 | |||||
| Study programme |
|
Cycle | 1st | |||||
| Descriptors | Credits | Type | Year | Period | ||||
| 6 | Basic Course | First | ||||||
| Competences | Learning outcomes | Contents |
| Planning | Methodologies | Personalized attention |
| Assessment | Sources of information | Recommendations |
| Topic | Sub-topic |
| 1. Introduction to Biochemistry |
Concept and scope of the study of Biochemistry. Levels of study. Methods of study. Biomolecules |
| 2. Structure of proteins. |
Levels of complexity. Primary structure, secondary structure, tertiary structure, quaternary structure. Denaturation and renaturation. Dynamics of proteins. |
| 3. Enzims | Enzymes as biocatalysts. Factors affecting enzyme activity. Enzyme-substrate interactions, models. Mechanisms of enzyme catalysis. Enzyme kinetics. Coenzymes and cofactors Modulation of enzyme activity. |
| 4. Transmission of information |
Nucleic acids. DNA replication process. DNA Transcription. Protein synthesis: The genetic code. Mechanism of translation. Regulation of gene expression |
| 5. Introduction to Metabolism |
Organization. Pathways and metabolic cycles. Anabolism and catabolism. Control of metabolic flux. Digestion and absorption of substrates in mammals |
| 6. Bioenergetics |
Thermodynamic and biological systems. The phosphate group of ATP and energy as intermediaries common. Coupled reactions. Substrate level phosphorylation and oxidative phosphorylation. |
| 7. Respiratory chain and oxidative phosphorylation |
Location. Redox reactions. Coupling between electron transport and ATP synthesis. Role of the shuttles. Electron transport in chloroplasts and photosynthetic phosphorylation. Photosynthesis. Photosystems. |
| 8. Cycle of tricarboxylic acids |
Central role in the intermediary metabolism. Reactions of the cycle. Energy performance. Anaplerotic reactions. Cycle regulation |
| 9. Metabolism of glucose |
General scheme. Global energy balance and universal importance. Stages of glycolysis. Fermentation. General regulation and energy efficiency. Pentose phosphate pathway Glucids biosynthesis. Gluconeogenesis. Metabolism of glycogen Calvin cycle. |
| 10. Lipid Metabolism |
Lipoprotein metabolism. Lipid catabolism. Beta-oxidation of fatty acids. Energy efficiency Ketogenesis. Lipid biosynthesis. Lipogenesis. Cholesterol synthesis. |
| 11. Metabolism of amino acids |
Catabolism. Deamination, transamination and transdeamination Organification and fixation of nitrogen. Essential amino acids and non-essential. NH3 metabolism. Urea cycle. Destination carbonate skeleton of amino acids. Gluconeogenic and ketogenic amino acids. Amino acids as precursors. Degradation of nucleotides. |
