2019_20
Educational guide 
Faculty of Chemistry
A A 
english 
Bachelor's Degree in Biochemistry and Molecular Biology (2009)
 Subjects
  BIOCOMPUTING
   Contents
Topic Sub-topic
1) Introduction Definition and field of study.
Bioinformatics Web sites (EBI-EMBL, NCBI, Expasy).
2) Introduction to the Linux operating system Introduction to the operating systems. Installing packages. Terminal for simple tasks.
3) Bioinformatics databases Bibliographic databases (PubMed, ISI Web of Knowledge), sequences databases (UniProt, GenBank). Other databases.
4) Search and sequence analysis Concept of homology. Pair-wise alignments (Needelman-Wunsch and Smith-Waterman algorithms). Dotplot. Substitution matrices (PAM, BLOSUM). Search for similar sequences (BLAST).
5) Multiple alignments and construction of phylogenetic trees Multiple sequence alignment programs (CLUSTAL). Databases derived from multialineaments (PROSITE). Methods of phylogenetic reconstruction. Visualization of phylogenetic trees.