2019_20
Educational guide 
Faculty of Chemistry
A A 
english 
Bachelor's Degree in Biochemistry and Molecular Biology (2009)
 Subjects
  CELL SIGNALLING AND CONTROL OF CELL FUNCTION
   Contents
Topic Sub-topic
Introduction: Need to control cell function. Mechanisms to control cell function. Basic principles of cell signalling.
2. Extracellular signals: How cells communicate. Hormones, cytokines, growth factors, neurotransmitters, ions, photons, other signals.
3. Receptors: Types of receptor. Overview of cell signalling.
4. G proteins and cyclic nucleotides: Family of G proteins and functions. AMPc and adenylate cyclase. GMPc and guanylyl cyclase. Phosphodiesterases.
5. Inositol phosphate and other membrane lipids: phospholipases A, C and D. Inositol 1, 4,5-triphosphate. Phosphatitidylcholine and arachidonic acid. Other molecules derived from lipids that act as signals.
6. Calcium: Calcium-dependent proteins. Calmodulin. Intracellular concentrations and calcium stores. Mechanisms that mobilize calcium.
7. Protein kinases and protein phosphatases: serine / threonine kinases. Tyrosine kinases. Mitogen-activated protein kinases. Phosphatases
8. Nuclear receptors: Families of nuclear receptors. DNA recognition. Ligand bonding.
9. Redox signaling. NO. ROS
10. Specific signalling mechanisms.