Educational guide Faculty of Chemistry |
english |
Bachelor's Degree in Biochemistry and Molecular Biology (2009) |
Subjects |
CELL SIGNALLING AND CONTROL OF CELL FUNCTION |
Contents |
IDENTIFYING DATA | 2019_20 |
Subject | CELL SIGNALLING AND CONTROL OF CELL FUNCTION | Code | 13214115 | |||||
Study programme |
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Cycle | 1st | |||||
Descriptors | Credits | Type | Year | Period | ||||
6 | Compulsory | Second |
Competences | Learning outcomes | Contents |
Planning | Methodologies | Personalized attention |
Assessment | Sources of information | Recommendations |
Topic | Sub-topic |
Introduction: Need to control cell function. Mechanisms to control cell function. Basic principles of cell signalling. | |
2. Extracellular signals: How cells communicate. Hormones, cytokines, growth factors, neurotransmitters, ions, photons, other signals. | |
3. Receptors: Types of receptor. Overview of cell signalling. | |
4. G proteins and cyclic nucleotides: Family of G proteins and functions. AMPc and adenylate cyclase. GMPc and guanylyl cyclase. Phosphodiesterases. | |
5. Inositol phosphate and other membrane lipids: phospholipases A, C and D. Inositol 1, 4,5-triphosphate. Phosphatitidylcholine and arachidonic acid. Other molecules derived from lipids that act as signals. | |
6. Calcium: Calcium-dependent proteins. Calmodulin. Intracellular concentrations and calcium stores. Mechanisms that mobilize calcium. | |
7. Protein kinases and protein phosphatases: serine / threonine kinases. Tyrosine kinases. Mitogen-activated protein kinases. Phosphatases | |
8. Nuclear receptors: Families of nuclear receptors. DNA recognition. Ligand bonding. | |
9. Redox signaling. NO. ROS | |
10. Specific signalling mechanisms. |