Educational guide School of Engineering |
english |
Bachelor's Degree in Biomedical Engineering (2017) |
Subjects |
BIOCHEMISTRY |
Contents |
IDENTIFYING DATA | 2019_20 |
Subject | BIOCHEMISTRY | Code | 17254011 | |||||
Study programme |
|
Cycle | 1st | |||||
Descriptors | Credits | Type | Year | Period | ||||
6 | Basic Course | Second |
Competences | Learning outcomes | Contents |
Planning | Methodologies | Personalized attention |
Assessment | Sources of information | Recommendations |
Topic | Sub-topic |
1. Introduction to Biochemistry | Concept and scope of the study of Biochemistry. Levels of study. Methods of study. Biomolecules |
2. Structure of proteins. | Levels of complexity. Primary structure, secondary structure, tertiary structure, quaternary structure. Denaturation and renaturation. Dynamics of proteins. |
3. Enzymes | Enzymes as biocatalysts. Factors affecting enzyme activity. Enzyme-substrate interactions, models. Mechanisms of enzyme catalysis. Enzyme kinetics. Coenzymes and cofactors Modulation of enzyme activity. |
4. Transmission of information | Nucleic acids. DNA replication process. DNA Transcription. Protein synthesis: The genetic code. Mechanism of translation. Regulation of gene expression |
5. Introduction to Metabolism | Organization. Pathways and metabolic cycles. Anabolism and catabolism. Control of metabolic flux. Digestion and absorption of substrates in mammals |
6. Bioenergetics | Thermodynamic and biological systems. The phosphate group of ATP and energy as intermediaries common. Coupled reactions. Substrate level phosphorylation and oxidative phosphorylation. |
7. Respiratory chain and oxidative phosphorylation | Location. Redox reactions. Coupling between electron transport and ATP synthesis. Role of the shuttles. Electron transport in chloroplasts and photosynthetic phosphorylation. Photosynthesis. Photosystems. |
8. Cycle of tricarboxylic acids | Central role in the intermediary metabolism. Reactions of the cycle. Energy performance. Anaplerotic reactions. Cycle regulation |
9. Metabolism of glucose | General scheme. Global energy balance and universal importance. Stages of glycolysis. Fermentation. General regulation and energy efficiency. Pentose phosphate pathway Glucids biosynthesis. Gluconeogenesis. Metabolism of glycogen Calvin cycle. |
10. Lipid Metabolism | Lipoprotein metabolism. Lipid catabolism. Beta-oxidation of fatty acids. Energy efficiency Ketogenesis. Lipid biosynthesis. Lipogenesis. Cholesterol synthesis. |
11. Metabolism of amino acids | Catabolism. Deamination, transamination and transdeamination Organification and fixation of nitrogen. Essential amino acids and non-essential. NH3 metabolism. Urea cycle. Destination carbonate skeleton of amino acids. Gluconeogenic and ketogenic amino acids. Amino acids as precursors. Degradation of nucleotides. |