2021_22
Educational guide 
Faculty of Oenology
A A 
 
Bachelor's Degree in Biotechnology (2009)
 Subjects
  TISSUE ENGINEERING
   Contents
Topic Sub-topic
1. Introduction to tissue engineering: History, cells and materials used. The challenge of imitating nature: the importance of the cellular microenvironment in functionality. Applications and future perspectives.
2. Homeostasis of tissues. Definition of the terms homeostasis, regeneration and tissue repair. Type of fabrics according to their regeneration capacity: Consequences of regeneration capacity in tissue engineering
3. Morphogenesis, generation of the tissue in the embryo. Morphogenesis and cell therapy. The desenvolupament of certain systems and organs: Examples: Application of the engineering of tissues in the generation of bone and articulation
4. Cell signalling. The basis of cell signalling. Receptors. Intracellular signalling. Protein phosphorilation and other covalent reversible modifications. Scarring process as an example of cell signalling
5. The extracellular matrix as a biological support for tissue engineering. Definition, composition and characteristics of the extracellular matrix. Role of the extracellular matrix in biological processes. Biological activity of the supports. future considerations
6. Cells sources. Stem cells. Basic concepts about stem cells, type, characteristics, origin and its regulation *. Techniques used for the generation of pluripotent stem cells (cellular reprogramming). Examples: application of stem cells in certain human diseases.
7. Biocompatibility. Definition. Evolution and current concept of Biocompatibility. The biocompatibility agents. Biocompatibility in tissue engineering.
8. Biomaterials. Definition. Classification and selection. Properties.
9.Examples of biomaterials. Polymers of biologic origin. Polymers of synthesis. Bioceramics.

10. Technologies for tissue fabrication. Scaffold-free methods. Scaffold-based systems.Cell and organ printing...
11. Bioreactors for tissue engineering. Functions of bioreactors in tissue engineering. Basic principles for the design of bioreactors and development. Type of bioreactors. Bioreactors in clinical applications. Examples. Future perspectives.