| Educational guide School of Chemical Engineering |
english |
| Nanoscience and Nanotechnology (2010) |
 Subjects |
| BIOCOMPUTING |
| Contents |
| IDENTIFYING DATA | 2012_13 |
| Subject | BIOCOMPUTING | Code | 20635214 | |||||
| Study programme |
|
Cycle | 2nd | |||||
| Descriptors | Credits | Type | Year | Period | ||||
| 2.5 | Optional | Only annual |
||||||
| Competences | Learning aims | Contents |
| Planning | Methodologies | Personalized attention |
| Assessment | Sources of information | Recommendations |
| Topic | Sub-topic |
| 1. Introduction. | What is bioinformatics? Fundamentals of structure of nucleic acids and proteins. Genome and proteome. The evolution at the molecular level. Distance matrices. Major databases of nucleic acids and proteins. Data mining in databases of molecular biology: the SRS. |
| 2. Sequence comparison. | Measures of similarity between two sequences. Alignment of two sequences. Multialignment Phylogenetic trees. Application of sequence comparison in data mining. |
| 3. Comparative analysis of genomes. | Analysis and annotation of genomes. Application of comparative genomics in the reconstruction of metabolic pathways. |
| 4. Structure / function of proteins relationship. | Fundamentals of experimental determination of protein structure. The PDB database: data mining and analysis in it the information contained therein. Analysis of protein structure using molecular visualization software. Structural evolution relationship and correlation with structure / function. Prediction function. Docking. |
| 5. Obtaining structural information of proteins of unknown structure. | Prediction of secondary structure. Prediction of folding. Homology modeling. |
| 6. Protein engineering. | Properties of the proteins that could be improved. Selection of mutations according to property improvement. Mutagenesis "in silico." |
| 7. Introduction to Perl Programming | Basic programming with PERL. Design of bioinformatics algorithms. |
