| Guia docent Escola Tècnica Superior d`Enginyeria Química |
català |
| Enginyeria Ambiental (2006) |
 Assignatures |
| FUNDAMENTALS ON MOLECULAR BIOPHYSICS |
| Continguts |
| DADES IDENTIFICATIVES | 2006_07 |
| Assignatura | FUNDAMENTALS ON MOLECULAR BIOPHYSICS | Codi | 205141234 | |||||
| Ensenyament |
|
Cicle | 2on | |||||
| Descriptors | Crèd. | Tipus | Curs | Període | ||||
| 3 | Optativa | Primer |
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| Competències | Objectius d'aprenentatge | Continguts |
| Planificació | Metodologies | Atenció personalitzada |
| Avaluació | Fonts d'informació | Recomanacions |
| Tema | Subtema |
| Fundamental concepts |
1. Questions and methods in biophysics 1.1 Physics and Biology 1.2 Causality and determinism 1.3 Properties of open systems 2. Fundamental chemistry in biophysics 2.1 Aminoacids 2.2 Electrolytes 2.3 Carbohydrates and lipids 2.4 Nucleid acids 2.5 Proteins 3. Geometry of a polymer chain 3.1 Radius of gyration 3.2 Constraints of the valence bond 3.3 Torsional potential 3.4 DNA flexibility 4. The Protein folding problem 4.1 Protein conformation 4.2 Folding mechanism 4.3 Protein stability 4.4 The structure and function relationship 4.5 Transition state theory 5. Thermodynamics in Biology 5.1 Information and Entropy 5.2 Non-equilibrium processes 5.3 Some mathematical aspects: flow equations, transition state models |
| Molecular forces |
6. Intermolecular forces between atoms and molecules 6.1 Van der Waals forces 6.2 Electrostatic forces 6.3 Hydrogend bonding 6.4 Hydrophobic and hydrophilic interactions 7. Intermolecular pair potentials 7.1 Size of atoms, molecules and ions 7.2 Repulsive potentials 7.3 Different intermolecular potentials 7.4 Liquid structure and molecular forces 8. Intermolecular forces between particles and surfaces 8.1 Unifying in intermolecular and interparticle forces 8.2 Differences between intermolecular, interparticle and intersurface forces 8.3 Van der Waals forces between surfaces 8.4 Electrostatic force between surfaces 8.5 Structural and hydration forces 8.6 Steric forces polymer at interfaces 9. Membranes 9.1 Cell membrane 9.2 Membrane transport 9.3 Molecular recognition |
| Experimental techniques applied to biological samples |
10 Structural methods 10.1 Microscopy: electron microscopy, confocal microscopy 10.2 Light scattering 10.3 Neutron and X-ray diffraction 10.4 Neutron and X-ray reflection 11 Spectroscopy 11.1 Circular dichroism 11.2 Fluorescence spectroscopy 11.3 Infrared spectroscopy 11.4 Raman spectroscopy 11.5 Nuclear magnetic resonance 12. Scanning force microscopy 12.1 Determining structure and molecular forces 12.1 Scanning tunnelling microscope (STM) 12.2 Atomic force microscope (AFM) 12.3 Combining AFM with spectroscopy, electrochemistry and classical optics 13. Measuring “biological” forces 13.1 Surface force apparatus 13.2 Thin film balance 13.3 Atomic force microscopy 13.4 Optical tweezers |
