| Educational guide Faculty of Chemistry |
english |
| Nutrition and Metabolism (2012) |
 Subjects |
| FUNDAMENTALS OF IMMUNOLOGY |
| Contents |
| IDENTIFYING DATA | 2018_19 |
| Subject | FUNDAMENTALS OF IMMUNOLOGY | Code | 13675246 | |||||
| Study programme |
|
Cycle | 2nd | |||||
| Descriptors | Credits | Type | Year | Period | ||||
| 3 | Optional | AN |
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| Competences | Learning aims | Contents |
| Planning | Methodologies | Personalized attention |
| Assessment | Sources of information | Recommendations |
| Topic | Sub-topic |
| Topic 1.- INTRODUCTION TO THE IMMUNE SYSTEM (3 h) |
History. Characteristics and properties of the immune system. Natural and acquired immunity: concept of antigen. Elements of the immune System: immunocompetent cell, molecules and lymphoid tissues. |
| Topic 2.- NATURAL OR INNATE IMMUNE RESPONSE (3 h) | Characteristics and elements. Physical, chemical and biological natural barriers. Phagocytosis. Complement system. Natural Killer cells (NK). Inflammation and inflammatory processes. |
| Topic 3.- ACUIRED OR SPECIFIC IMMUNE RESPONSE (I) (2,5 h) | Characteristics. Involved cells: lymphocytes and antigen-presenting cells. Antibodies: structure, isotopes, and features. Antigen receptors. Molecules of the major histocompatibility complex. |
| Topic 4.- ACUIRED OR SPECIFIC IMMUNE RESPONSE (II) (2,5 h) | Processing and antigen presentation. Activation and differentiation of lymphocytes T CD4+: effectors and memory. Polarization Th1/Th2. Immune response mediated by T CD8+ cells: cytotoxicity. Immune response mediated by cell B: humoral response. |
| Topic 5.- MUCOSAL IMMUNE SYSTEM (1 h) |
Structure of lymphoid tissue associated to the gut. Non-specific intestinal immune response. Specific immune response. IgA secretion. |
| Topic 6.- TOLERANCE AND REGULATION OF THE IMMUNE RESPONSE (1 h) |
Central tolerance. Peripheral tolerance. Anergy. Regulatory T cells. |
| Topic 7.- IMMUNOASSAY TECHNIQUES (2 h) |
Use of antibodies as laboratory reagents. Immunoassay techniques: ELISA, ELISPOT and associated techniques. Flow cytometry. Immunohistochemistry. Other assays. |
| Topic 8.- IMMUNOPATOLOGY (4 h) | Leukocyte quantitative alterations and immunodeficiency. Hypersensitivity reactions and allergies. Autoimmune diseases. Immunotherapy: vaccines. Transplants. |
