| Educational guide Faculty of Oenology |
english |
| Bachelor's Degree in Biotechnology (2009) |
 Subjects |
| IMMUNOLOGY |
| Contents |
| IDENTIFYING DATA | 2017_18 |
| Subject | IMMUNOLOGY | Code | 19204109 | |||||
| Study programme |
|
Cycle | 1st | |||||
| Descriptors | Credits | Type | Year | Period | ||||
| 6 | Compulsory | Third | 1Q |
|||||
| Competences | Learning outcomes | Contents |
| Planning | Methodologies | Personalized attention |
| Assessment | Sources of information | Recommendations |
| Topic | Sub-topic |
| 1. Introduction to Immunology | - Origin and historical evolution of Immunology - Generalities of the immune system - Immune cells - Immunity innate - Immunity acquired |
| 2. Immune system tissues | - Anatomical organization of the immune system - Primary lymphoid organs - Secondary lymphoid organs - Lymphatic flow |
| 3. Innate immunity and inflammation | - Inflammatory cell component - Soluble factors own to innate immunity - Dynamics and molecular bases of inflammation |
| 4. The complement system | - Components and nomenclature - Activation by the classic way - Activation by the alternative way - Activation via lectins - Membrane attack complex - Effector systems of the complement system - Integration and feedback of the complement system - Acute inflammatory response - Regulation of the Complement |
| 5. Antigens and recognition of antigens | - Concept and properties of antigens - Immunoglobulins (Ig): Characteristics and structure. - Isotips and functions of Ig |
| 6. Repertoire of Ig | - Ig gene segments - Somatic combinations - Diversity of union - Allelic exclusion - Concept of somatic hypermutation and change of isotype |
| 7. Presentation of antigens | - Structure and function of MHC-I and MHC-II - Genètica and MHC polymorphism - Expression of the MHC - Specificity of MHC and initiation of adaptive immunity |
| 8. Maturation and activation of B-lymphocytes | - B-lymphocyte markers during maturation - Expression of the BCR - Phenomena of lymphocyte selection - Central and peripheral tolerance - Accommodation and circulation of B lymphocytes - T-independent activation of B lymphocytes |
| 9. Maturation and activation of T-lymphocytes | - Gene organization and expression of the TCR - Co-receptors and co-stimulators - Thymic selection and peripheral tolerance - CD4 + / CD8 + differentiation - Immunological synapse |
| 10. APC-T-B collaboration | - Migration of T and B in the follicles - Activation of T-dependent B-cells - Germinal centers events - Switching or Ig isotype change - Maturation of Ig affinity (Hypermutation) - Differentiation of B-lymphocytes |
| 11. Cytokines | - Cytokines properties - Cytokines receptors - Cytokines functions - Anti- and proinflammatory cytokines - Regulatory effects of cytokines in adaptive responses |
| 12. Subpopulations of Lymphocytes | - Citotoxicity by T-CTL and NK cells - Differentiation Th1, Th2, Th17 and Treg - Effective and regulating functions of subpopulations T |
